A mysterious contagion devastates civilization. The infected are beyond count, and they are running out of victims upon which to feed. Outlaws are taking over as they plunder naïve survivors seeking shelter and protection from massing herds of mutated predators. Cowboy discovers his awakened abilities to detect the infected and keep them at bay, complicating both his shadowy past and uncertain present. Gloria establishes a refugee camp, relying on Cowboy's help to protect the few from the many. Luke and his father are on the run, joining others on a trek across the country, fleeing scramblers and criminals. Sebridge, a devious colonel plotting his own agenda amidst the chaos, holds Carly and Marik captive. Roger fights a lonely battle for survival, matching his wits against psychotic scoundrels and ravenous berserkers. Survival of humans and The Turned now hangs on a frightening, unyielding reality, jeopardizing the fate of all.